Did you try CronJobs ?

apiVersion: batch/v1beta1
kind: CronJob
metadata:
  name: hello
spec:
  schedule: "*/1 * * * *"
  jobTemplate:
    spec:
      template:
        spec:
          containers:
          - name: your_app_name
            image: your_image
            args:
            - your
            - args
          restartPolicy: OnFailure

It's official Kubernetes docs under cron jobs.

Also, here is a cron schedule expression editor that might be useful: crontab.guru.

From what I understand, there are two ways to achieve this. I'm assuming your app is running as a deployment in kubernetes, so deleting pod should create a new one.

1. Exit your node app after 48 hours i.e. exit from within your code, a dirty way, but it's simplest.
2. Create a cronjob that runs after 48 hours and delete any pod created under your deployment.